PrimaryUnuaranga liverhepatokancero cancerestas istutmonde globallyla thesesa sixth-mostplej frequentofta cancerkancero (6%) andkaj thela second-leadingdua causeĉefa ofkaŭzo deathde frommorto cancerpro kancero (9%).<ref name=WCR2014Liver/><ref name=WCR2014Epi>{{cite book|title=World Cancer Report 2014|date=2014|publisher=World Health Organization|isbn=978-9283204299|pages=Chapter 1.1}}</ref> InEn 2018, itĝi occurredokazis inen 841, 000 peopleperosnoj andkaj resultedrezultis inen 782, 000 deathsmortoj.<ref name=Bray2018>{{cite journal |last1=Bray |first1=F |last2=Ferlay |first2=J |last3=Soerjomataram |first3=I |last4=Siegel |first4=RL |last5=Torre |first5=LA |last6=Jemal |first6=A |title=Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. |journal=CA: A Cancer Journal for Clinicians |date=November 2018 |volume=68 |issue=6 |pages=394–424 |doi=10.3322/caac.21492 |pmid=30207593 |url=https://semanticscholar.org/paper/83ab5cf89399bca5449f4a7baf1b1b3c2e1178c7 |doi-access=free }}</ref> InEn 2015, 263, 000 deathsmortoj frompro liverhepatokancero cancerestis wereokazigitaj duede to hepatitishepatito B, 245, 000 tode alcoholalkoholo andkaj 167, 000 tode hepatitishepatito C.<ref name=GBD2015De>{{cite journal|last1=GBD 2015 Mortality and Causes of Death|first1=Collaborators.|title=Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015.|journal=Lancet|date=88a Octoberde oktobro 2016|volume=388|issue=10053|pages=1459–1544|pmid=27733281|doi=10.1016/s0140-6736(16)31012-1|pmc=5388903}}</ref> HigherPlej ratesaltaj ofindicoj liverde cancerhepatokancero occurokazas wherekie hepatitishepatito B andkaj C areestas commonkomunaj, includingkiel Asiaen andAzio kaj [[Subsahara Afriko]].<ref name=WCR2014Liver/> MalesMaskloj areestas moreplej oftenofte affectedatakitaj withde HCCHĈK thanol femalesinoj.<ref name=WCR2014Liver/> DiagnosisDiagnozo isestas mostplej frequentofta amonginter thosetiuj kiuj aĝas 55 toĝis 65 years oldjarojn.<ref name=SEER2016/> [[Five-yearLa survivalkvinjara rate]]survivindico isestas de 18.4 % in the Uniteden StatesUsono,<ref name=SEER2016>{{cite web|title=SEER Stat Fact Sheets: Liver and Intrahepatic Bile Duct Cancer|url=http://seer.cancer.gov/statfacts/html/livibd.html|website=NCI|url-status=live|archiveurl=https://web.archive.org/web/20170728014514/https://seer.cancer.gov/statfacts/html/livibd.html|archivedate=2017-07-28}}</ref> andkaj de 40.4% inen JapanJapanio.<ref name=Japan2011>{{cite web |title=がん診療連携拠点病院等院内がん登録生存率集計：[国立がん研究センター がん登録・統計] |url=https://ganjoho.jp/reg_stat/statistics/brochure/hosp_c_reg_surv.html |website=ganjoho.jp |accessdate=22a Februaryde februaro 2020}}</ref> The
La wordvortoj "hepatichepata" iskaj from"hepato" theestas el la [[Greka lingvo|greka]] ''hêpar'', meaningkun la signifo "liverhepato".<ref>{{cite web|url=http://dictionary.reference.com/browse/hepato-|title=''Hepato-'' Etymology|publisher= dictionary.com |accessdate=24a de oktobro 2015|url-status=live|archiveurl=https://web.archive.org/web/20151010044253/http://dictionary.reference.com/browse/hepato-|archivedate=10a de oktobro 2015}}</ref>
